POAPS videly utilizes chromatographic techniques in analytical and preparative goals. High resolution gas chromatography, HPLC, LC-MS/MS are applied for organic impurities investigation in biologycal samples.

Main core for biopolymers separation and purification are Pharmacia Biotech and GE Healthcare FPLC analytical and preparative FPLC systems, equipped with unique columns and media produced for biochemical and biotechnology applications.